Bringing the fundamentals into focus…
Back to Septerna, Inc.
How Septerna, Inc. stacks up
SEPN · against 1,335 other Healthcare companies
Profitability
25/ 100
Near the bottom of its peers.
Ranked #996 of 1,336 · scores higher than 25% of peers
Bars: peers in each 10-point band of the profitability score133 peers with a profitability score of 20–29, including SEPN · Click a bar to see the companies
Why profitability scores 25?
Weighted metrics compared with all Healthcare companies.Mainly because of its operating margin, return on invested capital and return on assets, which are weaker than most Healthcare peers.
- a thinner operating margin: weaker than 83% of peers. Operating margin: -44.0% vs peer median 7.1%
- a lower return on invested capital: weaker than 75% of peers. Return on invested capital: -11.4% vs peer median 4.7%
- a lower return on assets: weaker than 69% of peers. Return on assets: -4.3% vs peer median 1.7%
Metric by metric
Position: dot = SEPN, ranked from the worst peer (left) to the best (right); tick = middle, shaded = middle half of peers.| Metric | SEPN | Peer median | Better than | Position among peers | Weight |
|---|---|---|---|---|---|
| Return on invested capitalHigher is better · 1,226 reported | -11.4% | 4.7% | 25% | 33% | |
| Operating marginHigher is better · 1,251 reported | -44.0% | 7.1% | 17% | 33% | |
| Return on assetsHigher is better · 1,315 reported | -4.3% | 1.7% | 31% | 33% | |
| Return on equityHigher is better · 1,252 reported | -6.3% | 3.2% | 35% | Context only | |
| Gross marginHigher is better · 1,394 reported | 100.0% | 45.9% | 97% | Context only |
Ranking by profitability score
Top 5 and the companies ranked around SEPN| Rank | Company | Market cap | Profitability | Overall |
|---|---|---|---|---|
| 1 | 3.1B EUR (≈$3.4B) | 100 | 100 | |
| 1 | 321.5B INR (≈$3.9B) | 100 | 70 | |
| 1 | 174.8B INR (≈$2.1B) | 100 | 73 | |
| 1 | 97.3B INR (≈$1.2B) | 100 | 80 | |
| 5 | 12.3B CNY (≈$1.7B) | 99 | 85 | |
| 996 | 1.9B USD | 25 | 44 | |
| 996 | 578M USD | 25 | 22 | |
| 996 | 660M GBP (≈$858M) | 25 | 35 | |
| 996 | 191M USD | 25 | 38 | |
| 996 | 2.0B USD | 25 | 53 | |
| 996 | 14.0B USD | 25 | 31 | |
| 1,009 | 3.1B CNY (≈$438M) | 24 | 46 | |
| 1,009 | 2.8B CNY (≈$396M) | 24 | 29 | |
| 1,009 | 12.7B CNY (≈$1.8B) | 24 | 20 |
Scores are sector-relative percentiles from the latest snapshot, always calculated against the whole sector: narrowing the comparison group changes who you compare with, not the scores. Missing metrics are left out and the remaining weights rescaled. How we score