Price as of close on Nov 3, 2026 · Financials updated Oct 1, 2026
Basics
Sector
Healthcare
Industry
Biotechnology
Country
United States
Market cap
1.3B USD
Enterprise value
1.1B USD
Full-time employees
175
Overall health
Strength:its shares are priced lower than most peers relative to what it earnspriced lower than peers for its earnings
Drawback:less profitable than most peersless profitable than peers
Drawback:higher risk than most peers: its share price swings more than most peers’ (beta 2.60 vs a peer median of 0.63)higher risk: bigger price swings (beta 2.60 vs peers 0.63)
Not enough data: growth
Would rank #995 of 1,157 fully scored healthcare companies (bottom 15%)
Profitable, but burning cash. Reports a profit, but free cash flow is negative.
Omeros reports a profit but its free cash flow is negative: it spent more on investment and running the business than it brought in. That's common for companies building capacity, but it means the profit isn't yet turning into cash.
Paying shareholders without free cash flow. Paid out $17M over the 3 fiscal years to 2025 with -$191M of free cash flow.
Omeros returned $17M in buybacks and dividends over three fiscal years while its free cash flow totalled -$191M. The money came from its cash pile or from borrowing.
Negative shareholders' equity. Liabilities exceed assets on the balance sheet.
Omeros's liabilities exceed its assets on the balance sheet. Large share buybacks can cause this in healthy companies, but so can accumulated losses; either way, debt-based ratios need care.
Shareholders being diluted. Shares outstanding up 15% from December 2022 to August 2026.
Omeros had 15% more shares at August 2026 than at December 2022, mostly from issuing stock (for pay, acquisitions or fundraising). Each existing share now owns a smaller slice of the business.Omeros had 15% more shares at August 2026 than at December 2022, mostly from issuing stock. Each existing share now owns a smaller slice of the business.
Since last year: No major changeValuation also moves with the share price every day.
Why it changed since the Oct 27, 2026 close: Score 72 → 71
Share price +4.5%-1
Each step re-scores the company against its peers as they were on Oct 28, 2026; the parts add up to the change. Price effects on EBITDA yield are approximate.
Sector-normalized EBITDA, earnings, and free cash flow yields.
Earnings yield9.4%
SEC filings · 12 months to Jun 2026Reported value30% base weight · Z-score 5.38Sector median: 0.0148 · MAD: 0.0148
EBITDA yield-5.8%
SEC filings · 12 months to Jun 2026Negative (a loss or cash outflow), so it counts as zero whatever the share price50% base weight · Z-score -1.00Sector median: 0.0401 · MAD: 0.0401
Free cash flow yield-5.2%
SEC filings · 12 months to Jun 2026 · operating cash flow − capital spendingNegative (a loss or cash outflow), so it counts as zero whatever the share price20% base weight · Z-score 0.00Sector median: 0.0000 · MAD: 0.0000
Shareholders' equity is negative, so debt/equity counts as among the highest in its peer group33% base weight · Z-score -9.77Sector median: 0.2215 · MAD: 0.2039
Valuation, growth and profitability scores: higher is better. Risk: 0 is lower, 2 is higher. Risk is a relative proxy, not a bankruptcy probability. Scores depend on available sector peers.
Questions investors ask about Omeros
Is Omeros getting weaker?
Its latest SEC filing (Aug 12, 2026) showed no major changes. Its overall score is unchanged at 29/100 since Oct 28, 2026.
How is Omeros valued vs its peers?
Priced lower than most peers relative to what it earns. Valuation scores 71/100 against 1,393 healthcare peers.Earnings yield 9.4% vs a peer median of 1.5% (stronger than 93% of peers).Earnings yield 9.4% vs peers 1.5% (stronger than 93% of peers).EBITDA yield -5.8% vs a peer median of 4.0% (weaker than 100% of peers).EBITDA yield -5.8% vs peers 4.0% (weaker than 100% of peers).
Is Omeros growing?
Insufficient data: 1 of 3 inputs reported (at least 2 needed).
How profitable is Omeros?
Less profitable than most of its peers. Profitability scores 15/100 against 1,393 healthcare peers.Return on assets 43.5% vs a peer median of 1.7% (stronger than 95% of peers).Return on assets 43.5% vs peers 1.7% (stronger than 95% of peers).Return on invested capital -288.3% vs a peer median of 4.7% (weaker than 100% of peers).Return on invested capital -288.3% vs peers 4.7% (weaker than 100% of peers).
How risky is Omeros?
Higher risk relative to 1,393 healthcare peers, judged on debt, liquidity and share-price swings.Beta 2.60 vs a peer median of 0.63 (weaker than 100% of peers).Beta 2.60 vs peers 0.63 (weaker than 100% of peers). A relative measure, not a bankruptcy probability.
Latest filing: what changed
Year ended Jun 30, 2026 · filed Aug 12, 2026 · compared with the year ended Sep 30, 2021
No major changes
Worth watching: Omeros is in the bottom fifth of its sector on profitability. From 2021 to 2025, 63% of companies in that position posted a loss over the following year, against 4% for the top fifth.
Previous year
Latest year
Change
Net income (12 months)
86.2M USD
124.8M USD
+44.9%
Free cash flow (12 months)
−94.8M USD
−68.7M USD
−27.5%
Debt
52.8M USD
73.3M USD
+38.8%
Cash
1.9M USD
2.0M USD
+4.3%
Shares outstanding
72.4M
72.4M
+0.0%
From the company’s own SEC filings, as filed. Twelve-month figures roll forward one year at a time.
Industry valuation context
Industry: Biotechnology · 132 companies
Valuations in Biotechnology are within their usual range since 2016.
48% of months since 2016 were valued lower than now.
22% of companies are in the most expensive fifth of their own price-to-sales history.
Median price-to-sales is +530% vs the whole market, against a usual +637%.
2016Shaded: most expensive fifth of its range2026
Earnings-based measures are left out for now because many companies in Biotechnology are losing money.
Describes valuations since 2016; it does not predict prices. US companies worth $1B+, from SEC filings and month-end prices, as of Aug 2026. Today's companies and industry labels are used throughout. Measured on sales and book value yields. How this works
Financials
Fiscal years from SEC annual filings · change vs the prior year
Key ratios
FY 2021
FY 2022
FY 2023
FY 2024
FY 2025
Change
Gross margin
—
—
—
—
—
—
Operating margin
—
—
—
—
—
—
Net margin
—
—
—
—
—
—
Return on assets (ROA)
46.3%
8.0%
-31.1%
-56.6%
-1.0%
▲ 56 pts
Return on equity (ROE)
816.8%
55.3%
—
—
—
—
Free cash flow margin
—
—
—
—
—
—
Current ratio
4.79×
3.25×
4.09×
1.69×
2.76×
▲ 64%
Quick ratio
—
—
—
—
—
—
Debt to equity
13.18×
3.68×
—
—
—
—
Interest coverage
-8.83×
-7.20×
-5.33×
-6.77×
-127.91×
▼ >999%
OMER price history
Price history is added with the daily price update and will appear after the next one.