Bringing the fundamentals into focus…
Back to Ionis Pharmaceuticals, Inc.
How Ionis Pharmaceuticals, Inc. stacks up
IONS · against 203 other Healthcare companies of similar size
Profitability
20/ 100
Near the bottom of its peers.
Ranked #178 of 204 · scores higher than 11% of peers
Bars: peers in each 10-point band of the profitability score22 peers with a profitability score of 20–29, including IONS · Click a bar to see the companies
Why profitability scores 20?
Weighted metrics compared with all Healthcare companies.Mainly because of its operating margin, return on invested capital and return on assets, which are weaker than most Healthcare peers.
- a thinner operating margin: weaker than 85% of peers. Operating margin: -68.0% vs peer median 7.1%
- a lower return on invested capital: weaker than 81% of peers. Return on invested capital: -24.7% vs peer median 4.7%
- a lower return on assets: weaker than 80% of peers. Return on assets: -18.9% vs peer median 1.7%
Metric by metric
Position: dot = IONS, ranked from the worst peer (left) to the best (right); tick = middle, shaded = middle half of peers.| Metric | IONS | Peer median | Better than | Position among peers | Weight |
|---|---|---|---|---|---|
| Return on invested capitalHigher is better · 196 reported | -24.7% | 9.1% | 13% | 33% | |
| Operating marginHigher is better · 190 reported | -68.0% | 12.6% | 8% | 33% | |
| Return on assetsHigher is better · 195 reported | -18.9% | 3.9% | 14% | 33% | |
| Return on equityHigher is better · 190 reported | -105.5% | 8.4% | 6% | Context only | |
| Gross marginHigher is better · 214 reported | -6.9% | 51.0% | 2% | Context only |
Ranking by profitability score
Top 5 and the companies ranked around IONS| Rank | Company | Market cap | Profitability | Overall |
|---|---|---|---|---|
| 1 | 3.1B EUR (≈$3.4B) | 100 | 100 | |
| 1 | 321.5B INR (≈$3.9B) | 100 | 70 | |
| 3 | 3.8B USD | 99 | 71 | |
| 3 | 20.0B AUD (≈$13.2B) | 99 | 77 | |
| 5 | 548.2B INR (≈$6.6B) | 98 | 68 | |
| 174 | 9.2B USD | 21 | 39 | |
| 174 | 9.3B USD | 21 | 29 | |
| 178 | 3.4B USD | 20 | 17 | |
| 178 | 4.7B USD | 20 | 46 | |
| 178 | 6.7B USD | 20 | 19 | |
| 178 | 7.8B USD | 20 | 30 | |
| 182 | 4.5B USD | 16 | 33 | |
| 182 | 4.0B USD | 16 | 30 | |
| 182 | 6.0B USD | 16 | 32 |
Scores are sector-relative percentiles from the latest snapshot, always calculated against the whole sector: narrowing the comparison group changes who you compare with, not the scores. Missing metrics are left out and the remaining weights rescaled. How we score